Author

Fotios Koumpouras

Yale UniversityORCID 0000-0002-4530-7626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Akiko IwasakiiD· 1 shared Alicia J. LittleiD· 1 shared Brett KingiD· 1 shared Christine J. KoiD· 1 shared Edward H. DohertyiD· 1 shared Emily Baker· 1 shared Helen Q. Cai· 1 shared Hong‐Jai ParkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Akiko IwasakiORCID

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2 papers

Recent·Most cited

Lupus Immune Complexes Drive Distinct Pro-Inflammatory Monocyte and Macrophage Populations Independent of Type I Interferon

Lais Osmani, Min Sun Shin, Sang Jin Lee, Helen Q. Cai, Won Jae Seong, Hyoungsu Kim, Jongjin Yoo, M. J. Kim, William Bracamonte, Mario Felix, Jong Gyun Ahn, Hong‐Jai Park, Junghee J. Shin, Serhan Ünlü, Jennefer Par‐Young, , Insoo Kang

This study identifies pro-inflammatory monocyte and macrophage subsets driven by lupus immune complexes, independent of type I interferon signaling, using scRNA-seq and proteomic analysis.

bioRxiv · Apr 24, 2026 · PreprintImmunology

Cutaneous lupus features specialized stromal niches and altered retroelement expression

Jeff R. Gehlhausen, Yong Kong, Emily Baker, Sarika M. Ramachandran, Fotios Koumpouras, Christine J. Ko, Matthew D. Vesely, Alicia J. Little, William Damsky, Brett King, Akiko Iwasaki

This study uses single-cell and spatial sequencing to identify interferon-driven pathways and retroelement expression in cutaneous lupus, showing their association with disease pathology.

Journal of Investigative Dermatology · May 21, 2025Peer-reviewedImmunology