Author

Sina W. Kürschner

Heidelberg UniversityORCID 0000-0002-4546-9684Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:plant (other)· 1 Assay:proteomics· 1 Approach:simulation· 1

Frequent Co-Authors

Manuel WinkleriD· 2 shared Philipp-Sebastian Reiners-KochiD· 2 shared Andreas ButtenschöniD· 1 shared Anna Babin-Ebell Gonçalves· 1 shared Björn Hartleben· 1 shared Charlotta FunayaiD· 1 shared Chi-Chung Wu· 1 shared Constanze SchmidtiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSystems Biology

Manuel WinklerORCID

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2 papers

Recent·Most cited

The interplay between biomechanics and cell kinetics explains the spatial pattern in liver fibrosis

Jieling Zhao, Seddik Hammad, Mathieu de Langlard, Pia Erdoesi, Yueni Li, Paul Van Liedekerke, Andreas Buttenschön, Manuel Winkler, Sina W. Kürschner, Philipp-Sebastian Reiners-Koch, Niels Grabe, Björn Hartleben, Stephanie D. Wolf, Johannes Georg Bode, Jan Georg Hengstler, , Dirk Drasdo

This paper develops a digital twin model to simulate liver fibrosis patterns, showing that ECM distribution results from cell death zones and biomechanical compression.

bioRxiv · Jul 31, 2025 · PreprintSystems Biology

A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells

Anna Babin-Ebell Gonçalves, Yifang Mao, Tinja Baljkas, Felix Wiedmann, Larissa Eis, Franziska Pilz, Manuel Winkler, Sina W. Kürschner-Zacharias, Marlene Hoffarth, Charlotta Funaya, Réza Shahidi, Cyrill Géraud, Chi-Chung Wu, Constanze Schmidt, Sergij Goerdt, , Mahak Singhal

This paper introduces a perfusion-independent method to isolate liver sinusoidal endothelial cells with high purity and throughput, comparable to perfusion-dependent methods.

bioRxiv · Mar 11, 2024Physiology