Author

Laura Tovini

Universidade Católica PortuguesaORCID 0000-0002-4548-2811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Catarina PenedaiD· 2 shared Raquel A OliveiraiD· 2 shared Catarina PedroiD· 1 shared Inês MilagreiD· 1 shared Mia Maesano Krapinec· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersCell Biology

Catarina PenedaORCID

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2 papers

Recent·Most cited

TTF2 prevents premature rRNA synthesis during mitotic exit

Catarina Pedro, Laura Tovini, Catarina Peneda, Mia Maesano Krapinec, Raquel A Oliveira

This study shows TTF2 prevents premature rRNA synthesis during mitotic exit by regulating RNA Polymerase I reactivation and nucleolar protein recruitment.

bioRxiv · Mar 23, 2026 · PreprintCell Biology

Removal of nascent transcripts by TTF2 is required for sister chromatid resolution in human cells.

Laura Tovini, Inês Milagre, Catarina Peneda, Raquel A Oliveira

This study shows that TTF2 removal causes mitotic defects by retaining transcription on chromatin, leading to sister chromatid resolution failure and genome instability.

bioRxiv · Feb 14, 2026 · PreprintCell Biology