Tunneling nanotubes mediate mitochondrial homeostasis in cancer
Inés Sáenz‐de‐Santa‐María, Anna Pepe, Christel Brou, Jean-Yves Tinévez, Yakov A. Vitrenko, Thomas Cokelaer, Elizabeth Cohen‐Jonathan Moyal, Roberto Weigert, Chiara Zurzolo
This study shows bidirectional mitochondrial transfer via tunneling nanotubes between glioblastoma cells and astrocytes, both in vitro and in vivo, and highlights their role in tumor microenvironment interactions.
bioRxiv · Jun 15, 2026 · PreprintCancer Biology