Roberto Weigert

This paper introduces iSiMM, a method for tracking single molecules in live tissues, and demonstrates its application to study protein dynamics in mice.

This study shows bidirectional mitochondrial transfer via tunneling nanotubes between glioblastoma cells and astrocytes, both in vitro and in vivo, and highlights their role in tumor microenvironment interactions.

This study identifies two spatially distinct myosin II architectures in neutrophils that coordinate protrusion dynamics and directional persistence during migration.

The paper identifies Gs pathway inactivation as an SMO-independent Hedgehog signaling driver in BCC and shows adenosine 2B receptor activation can counteract SMO-driven oncogenesis.

The paper tracks premalignant lesions in head and neck cancer using intravital microscopy and identifies myeloid cell organization as a predictor of lesion regression or progression.

This study shows that Net1 mRNA localization at the dermal-epidermal junction influences epithelial tissue organization by regulating RhoA activity and DEJ structure.

This study shows TRAIL treatment of TNBC cells activates the NFKB2 pathway, leading to cytokine production that enhances neutrophil chemotaxis and immune suppression.

This study shows that Cdc42 depletion in mice causes apical canaliculi expansion or inhibition, revealing its role in endocytosis regulation during tubular organ development.