Author

Faridoddin Mirshahi

Virginia Commonwealth UniversityORCID 0000-0002-4573-111XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Arun Jayant SanyaliD· 3 shared Mulugeta SeneshawiD· 3 shared Damian C. GenetosiD· 2 shared Galen GoldscheitteriD· 2 shared Henry J. DonahueiD· 2 shared Allison IpiD· 1 shared Amy L. OlexiD· 1 shared Austin Coelho· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersPhysiology

Arun Jayant SanyalORCID

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3 papers

Recent·Most cited

PNPLA3I148M is a novel regulator of bone mass independent of MASLD

Galen Goldscheitter, Mulugeta Seneshaw, Faridoddin Mirshahi, Morgan Summerlin, Allison Ip, Austin Coelho, Ronnie Li, Damian C. Genetos, Arun Jayant Sanyal, Henry J. Donahue

The paper investigates the effect of PNPLA3I148M on bone mass in a mouse model, finding it causes bone loss and alters bone metabolism independently of MASLD.

bioRxiv · Mar 17, 2026 · PreprintPhysiology

Sexual dimorphism of MASLD-driven bone loss

Galen Goldscheitter, Mulugeta Seneshaw, Faridoddin Mirshahi, Evan G. Buettmann, Damian C. Genetos, Arun Jayant Sanyal, Henry J. Donahue

This study investigates sex differences in bone loss associated with MASLD using DIAMOND mice, identifying potential liver-secreted factors involved in bone resorption.

Scientific Reports · Jul 1, 2025Peer-reviewedPhysiology

Anti-tumor immunity relies on targeting tissue homeostasis through monocyte-driven responses rather than direct tumor cytotoxicity

Nicholas James Koelsch, Faridoddin Mirshahi, Hussein F. Aqbi, Mulugeta Seneshaw, Michael O. Idowu, Amy L. Olex, Arun Jayant Sanyal, Masoud H. Manjili

The paper shows that anti-tumor immunity in HCC relies on monocyte-driven tissue homeostasis rather than direct tumor cytotoxicity, highlighting the importance of restoring liver integrity.

Liver International · Apr 24, 2025Peer-reviewedImmunology