Author

Henry J. Donahue

Virginia Commonwealth UniversityORCID 0000-0002-9238-4157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Arun Jayant SanyaliD· 2 shared Damian C. GenetosiD· 2 shared Faridoddin MirshahiiD· 2 shared Galen GoldscheitteriD· 2 shared Mulugeta SeneshawiD· 2 shared Abdullah AboodiD· 1 shared Allison IpiD· 1 shared Austin Coelho· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

Arun Jayant SanyalORCID

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3 papers

Recent·Most cited

PNPLA3I148M is a novel regulator of bone mass independent of MASLD

Galen Goldscheitter, Mulugeta Seneshaw, Faridoddin Mirshahi, Morgan Summerlin, Allison Ip, Austin Coelho, Ronnie Li, Damian C. Genetos, Arun Jayant Sanyal, Henry J. Donahue

The paper investigates the effect of PNPLA3I148M on bone mass in a mouse model, finding it causes bone loss and alters bone metabolism independently of MASLD.

bioRxiv · Mar 17, 2026 · PreprintPhysiology

Sexual dimorphism of MASLD-driven bone loss

Galen Goldscheitter, Mulugeta Seneshaw, Faridoddin Mirshahi, Evan G. Buettmann, Damian C. Genetos, Arun Jayant Sanyal, Henry J. Donahue

This study investigates sex differences in bone loss associated with MASLD using DIAMOND mice, identifying potential liver-secreted factors involved in bone resorption.

Scientific Reports · Jul 1, 2025Peer-reviewedPhysiology

Genetic Variability affects the Skeletal Response to Unloading

Michael A. Friedman, Abdullah Abood, Bhavya Senwar, Yue Zhang, Camilla Reina Maroni, Virginia L. Ferguson, Charles R. Farber, Henry J. Donahue

The paper shows genetic differences affect bone loss in mice under unloading, with specific strains showing greater bone volume and strength loss.

Bone Reports · Oct 12, 2021Peer-reviewedGenetics