Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy
Kristen R. Whitney, Won‐Min Song, Abhijeet Sharma, Diana K. Dangoor, Kurt W. Farrell, Margaret M. Krassner, Hadley W. Ressler, Thomas D. Christie, Shrishtee Kandoi, Ruth Helen Walker, Melissa Jill Nirenberg, Steven J. Frucht, Giulietta Maria Riboldi, Bin Zhang, Ana C. Pereira, John F. Crary
The paper uses single-nucleus RNA sequencing to analyze PSP brains and identifies dysregulation of the integrated stress response in vulnerable cell types.
Acta Neuropathologica · Dec 8, 2024Peer-reviewedNeuroscience