Author

Thomas D. Christie

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Diana K. Dangoor· 2 shared Hadley W. RessleriD· 2 shared John F. CraryiD· 2 shared Kristen R. WhitneyiD· 2 shared Kurt W. FarrelliD· 2 shared Margaret M. KrassneriD· 2 shared Melissa Jill NirenbergiD· 2 shared Ruth Helen WalkeriD· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Diana K. Dangoor

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2 papers

Recent·Most cited

Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy

Kristen R. Whitney, Won‐Min Song, Abhijeet Sharma, Diana K. Dangoor, Kurt W. Farrell, Margaret M. Krassner, Hadley W. Ressler, Thomas D. Christie, Shrishtee Kandoi, Ruth Helen Walker, Melissa Jill Nirenberg, Steven J. Frucht, Giulietta Maria Riboldi, Bin Zhang, Ana C. Pereira, John F. Crary

The paper uses single-nucleus RNA sequencing to analyze PSP brains and identifies dysregulation of the integrated stress response in vulnerable cell types.

Acta Neuropathologica · Dec 8, 2024Peer-reviewedNeuroscience

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

Kurt W. Farrell, Jack Humphrey, Timothy S. Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa, Vishakha Patil, Wan‐Ping Lee, Amanda B Kuzma, Otto Valladares, Laura B. Cantwell, Hui Wang, Ashvin Ravi, Claudia De Sanctis, Natalia Han, , Adam Naj

This study identifies six genetic loci associated with progressive supranuclear palsy, including a novel locus, and links them to oligodendrocytic dysfunction and C4A expression.

Nature Communications · Sep 9, 2024Peer-reviewedNeuroscience