Author

Abhijeet Sharma

Icahn School of Medicine at Mount SinaiORCID 0009-0001-2137-6563Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:machine learning (classical)· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Ana C. PereiraiD· 3 shared John F. CraryiD· 3 shared Kristen R. WhitneyiD· 3 shared Kurt W. FarrelliD· 3 shared Won‐Min SongiD· 2 shared Alison GoateiD· 1 shared Benjamin M. Jadow· 1 shared Bin ZhangiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Ana C. PereiraORCID

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3 papers

Recent·Most cited

Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy

Kristen R. Whitney, Won‐Min Song, Abhijeet Sharma, Diana K. Dangoor, Kurt W. Farrell, Margaret M. Krassner, Hadley W. Ressler, Thomas D. Christie, Shrishtee Kandoi, Ruth Helen Walker, Melissa Jill Nirenberg, Steven J. Frucht, Giulietta Maria Riboldi, Bin Zhang, Ana C. Pereira, John F. Crary

The paper uses single-nucleus RNA sequencing to analyze PSP brains and identifies dysregulation of the integrated stress response in vulnerable cell types.

Acta Neuropathologica · Dec 8, 2024Peer-reviewedNeuroscience

Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD

Kathryn R. Bowles, Derian A. Pugh, Laura‐Maria Oja, Benjamin M. Jadow, Kurt W. Farrell, Kristen R. Whitney, Abhijeet Sharma, Jonathan D. Cherry, Towfique Raj, Ana C. Pereira, John F. Crary, Alison Goate

The paper identifies dysregulated coordination of MAPT exon 2 and exon 10 splicing in Alzheimer's and progressive supranuclear palsy, leading to distinct tau isoform accumulation.

Acta Neuropathologica · Dec 7, 2021Peer-reviewedNeuroscience

Single-cell atlas of progressive supranuclear palsy reveals a distinct hybrid glial cell population

Abhijeet Sharma, Won‐Min Song, Kurt W. Farrell, Kristen R. Whitney, Bin Zhang, John F. Crary, Ana C. Pereira

The paper analyzes single-cell transcriptomic data from PSP brains to identify hybrid glial cell populations and their role in disease progression.

bioRxiv · Apr 11, 2021 · PreprintNeuroscience