Author

Melissa Jill Nirenberg

James J. Peters VA Medical CenterORCID 0000-0003-3892-6733Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:GWAS / association mapping· 2 Assay:scRNA-seq· 2 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

John F. CraryiD· 3 shared Ruth Helen WalkeriD· 3 shared Claudia De SanctisiD· 2 shared Diana K. Dangoor· 2 shared Hadley W. RessleriD· 2 shared Kristen R. WhitneyiD· 2 shared Kurt W. FarrelliD· 2 shared Margaret M. KrassneriD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

John F. CraryORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintOct 28, 2026

Parkinson's disease genetic risk converges on Lewy body pathology-associated microglial states

Raphael Kübler, Daniele Mattei, Josep Oriol Narcís…·Towfique Raj

The paper identifies microglial states associated with Parkinson's disease genetic risk and Lewy body pathology using single-cell profiling and integrates data with AMP PD.

DOI 10.64898/2026.10.26.26364188

humanscRNA-seq

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NeuroscienceActa NeuropathologicaPeer-reviewedDec 8, 2024

Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy

Kristen R. Whitney, Won‐Min Song, Abhijeet Sharma…·John F. Crary

The paper uses single-nucleus RNA sequencing to analyze PSP brains and identifies dysregulation of the integrated stress response in vulnerable cell types.

23 citationstop 2%

humanscRNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedSep 9, 2024

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

Kurt W. Farrell, Jack Humphrey, Timothy S. Chang…·Adam Naj

This study identifies six genetic loci associated with progressive supranuclear palsy, including a novel locus, and links them to oligodendrocytic dysfunction and C4A expression.

54 citationstop 1%

humanGWAS summary statistics

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