Author

Sandrine Vadon‐Le Goff

Lyon 1 UniversitéORCID 0000-0002-4582-2273Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

Catherine MoaliiD· 3 shared Cindy DieryckxiD· 2 shared Loïc CarriqueiD· 2 shared Priscillia LagoutteiD· 2 shared Camille Callies· 1 shared Emmanuel BettleriD· 1 shared Hok-Sau KwongiD· 1 shared Jean‐Baptiste VincourtiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

Catherine MoaliORCID

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Author profile →

3 papers

Recent·Most cited

A recombinant heterotrimeric mini-procollagen I reveals new functional and structural roles for the α2(I) chain

Oskar Lipinski, Cindy Dieryckx, Natacha Mariano, Priscillia Lagoutte, Hok-Sau Kwong, Sandrine Vadon‐Le Goff, Loïc Carrique, Catherine Moali

This study produces and characterizes recombinant procollagen I variants to elucidate the functional role of the α2(I) chain in fibril formation and proteolytic processing.

bioRxiv · Oct 6, 2026 · PreprintBiochemistry

Structure of PCPE-2 in complex with the BMP-1 metalloprotease reveals the molecular basis of its mechanism of inhibition

Julien Bauer, Priscillia Lagoutte, Jonathan Vaneyck, Valeria Calvaresi, Emmanuel Bettler, Mireille Dumoulin, Catherine Moali, Loïc Carrique, Sandrine Vadon‐Le Goff

The paper determines the structure of PCPE-2 bound to BMP-1, revealing how PCPE-2 inhibits BMP-1 through a bipartite interaction involving its CUB domains.

bioRxiv · Sep 23, 2026 · PreprintBiochemistry

Distinct regulation of collagen biosynthesis by hypoxia and vitamin C uncovers an essential role for CXCL12-CXCR4 signaling

Méline Ricol, Cindy Dieryckx, Camille Callies, Sandrine Vadon‐Le Goff, Jean‐Baptiste Vincourt, Catherine Moali, Violaine Sée

This study shows that ascorbic acid and hypoxia regulate collagen biosynthesis through distinct mechanisms, with AA enhancing secretion via CXCL12-CXCR4 signaling and hypoxia increasing hydroxylation.

bioRxiv · Sep 17, 2026 · PreprintCell Biology