Author

Willem de Koning

Erasmus MCORCID 0000-0002-4594-8423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Agnieszka Katarzyna MaciołaiD· 1 shared Alfredo Pherez-FarahiD· 1 shared Andew Stubbs· 1 shared Anne Onrust-van SchoonhoveniD· 1 shared Bram W. van OsiD· 1 shared Casper H.J. van Eijck· 1 shared Casper W.F. van Eijck· 1 shared Edoardo PeroniiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

Agnieszka Katarzyna MaciołaORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 20, 2026

Antigen recognition licenses therapeutic CD8+ T cells to organize a multicellular myeloid interaction network in the tumor microenvironment

Alfredo Pherez-Farah, Willem de Koning, Weisha Qi…·Giulia Pasqual

This study investigates how therapeutic CD8+ T cells interact with myeloid cells in the tumor microenvironment through antigen recognition, revealing state-selective networks and the role of pMHC-I sources.

DOI 10.64898/2026.10.14.759124

humanscRNA-seq

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ImmunologyJournal of Allergy and Clinical ImmunologyPeer-reviewedJun 17, 2026

Common γ-chain cytokines induce an epigenomically plastic precursor-like KIT+ ILC2 state linked to immune disease susceptibility

Simone E. M. Olsthoorn, Anne Onrust-van Schoonhoven, Marjolein J. W. de Bruijn…·Ralph Stadhouders

This study identifies KIT+ ILC2s as an epigenomically plastic state linked to immune disease susceptibility and shows that STAT5 activation by cytokines induces this phenotype.

1 citation

humanbulk RNA-seq

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Cancer BiologyCancer Treatment and Research CommunicationsPeer-reviewedJan 1, 2026

Bulk RNA sequencing deconvolution of pancreatic ductal adenocarcinoma identifies cancer-associated fibroblast subsets associated with survival and tumor microenvironment composition

Nicole Dam, Mischa F.B. Steketee, Gaby J. Strijk…·Bram W. van Os

The paper uses bulk RNAseq deconvolution to identify CAF subtypes in early onset PDAC and links their abundance to survival and tumor microenvironment composition.

DOI 10.1016/j.ctarc.2026.101490

humanbulk RNA-seq

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