Author

B. Timothy Hummer

AstraZeneca (United Kingdom)ORCID 0000-0002-4601-7487Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Anton I. RosenbaumiD· 1 shared ChaoYu Jin· 1 shared Joseph S. GrimsbyiD· 1 shared Kristina S. KovacinaiD· 1 shared Meina LiangiD· 1 shared Ruipeng Mu· 1 shared Yue HuangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anton I. RosenbaumORCID

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1 paper

Recent·Most cited

Inhibition of Endothelial Lipase by MEDI5884 Normalizes Phosphatidylinositol Levels in Coronary Artery Disease Patients

Anton I. Rosenbaum, Yue Huang, Ruipeng Mu, Kristina S. Kovacina, ChaoYu Jin, B. Timothy Hummer, Meina Liang, Joseph S. Grimsby

This study shows that MEDI5884 increases phosphatidylinositol levels in CAD patients by inhibiting endothelial lipase, correlating with improved HDL function and reverse cholesterol transport.

bioRxiv · May 30, 2024 · PreprintPharmacology & Toxicology