Joseph L. DeRisi

This study uses metagenomic sequencing to detect respiratory pathogens in hematopoietic transplant patients, finding it more sensitive than conventional methods and identifying new pathogens.

This study compares metagenomic DNA sequencing with pathogen-directed PCR for diagnosing intraocular infections, finding DNA-seq detects more pathogens and identifies drug resistance mutations.

MinorityReport identifies genetic variants between two genome alignments to detect causal mutations in drug resistance or genotype-phenotype relationships.