Author

Monica T. Dayao

University of California, San FranciscoORCID 0000-0002-5649-6784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Bioinformatics· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Assay:proteomics· 3 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Joseph L. DeRisiiD· 5 shared Aaron BodanskyiD· 4 shared Bryan Castillo-RojasiD· 3 shared James AsakiiD· 3 shared Michael R. WilsoniD· 3 shared Chung-Yu Wang· 2 shared Mark Stuart AndersoniD· 2 shared Samuel J. PleasureiD· 2 shared

Activity by Year

2026-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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5 shared papersImmunology

Joseph L. DeRisiORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Genome-wide within-host evolution during prolonged SARS-CoV-2 infection in a person with advanced HIV infection

Karina Perlaza, Ishaan Dureja, Diane V. Havlir, Vivek Jain, Jeffrey D. Whitman, Monica T. Dayao, Bryan Castillo-Rojas, Julia Rosecrans, Mélanie Ott, Carina Marquez, Joseph L. DeRisi, Taha Y. Taha

The paper tracks SARS-CoV-2 mutations over 90 days in an HIV-positive individual and tests their functional impact on viral entry and replication.

bioRxiv · Oct 8, 2026 · PreprintMicrobiology

Longitudinal linear-epitope profiling of SLE identifies novel antigens associated with disease and disease activity

Charlotte Hurabielle, Yutong V Wang, Bryan Castillo-Rojas, Chung-Yu Wang, Colette M. Caspar, James Asaki, Monica T. Dayao, Max Calcoen, Eric Dean Merrill, Aaron Bodansky, Arielle L. Klepper, Elizabeth N Chung, Caroline B. Vissers, Kelsey C. Zorn, Mark Stuart Anderson, , Joseph L. DeRisi

This study identifies novel SLE autoantigens and links EBV-driven immunity to autoimmunity through longitudinal PhIP-seq and machine learning analysis.

bioRxiv · Oct 4, 2026 · PreprintImmunology

AEGIS reveals epitope- and clone-resolved convergence of CNS B and T cell autoreactivity in ROHHAD

Aaron Bodansky, Vida Ahyong, Monica T. Dayao, James Asaki, ShiLu Vanasupa, Ravi Dandekar, Shini Chen, Joe Sabatino, Sam Klauer, Giselle M. Knudsen, Carlos Lizama Valenzuela, Krista Mccutcheon, Kelsey Zorn, Sukhman Sidhu, David Yu, , Joseph L. DeRisi

AEGIS identifies epitope- and clone-specific autoimmunity in ROHHAD by linking immune repertoires to self-epitopes, revealing convergence on ZSCAN1 epitopes in the CNS.

bioRxiv · May 11, 2026 · PreprintImmunology

ORION: An agentic reasoning construct for the analysis of complex human immune profiling

Monica T. Dayao, Kenny Kim, Bernard Khor, Aaron Jaech, Bas van Opheusden, Aaron Bodansky, Joseph L. DeRisi

ORION uses AI to analyze immune profiling data, reducing analysis time from months to hours and generating testable hypotheses.

bioRxiv · Apr 16, 2026 · PreprintBioinformatics

Structure-guided design of a targeted autoantibody degrader for neurologic disease

Marcell Zimanyi, Monica T. Dayao, Andoni I. Asencor, Sravani Kondapavulur, James Asaki, Krista M. McCutcheon, Cristina Dabaco, Aaron Bodansky, Charles S. Craik, Samuel J. Pleasure, Joseph L. DeRisi, Yifan Cheng, Michael R. Wilson, John V. Pluvinage

This paper designs a targeted autoantibody degrader to treat neurologic diseases by specifically clearing pathogenic autoantibodies while preserving the immune system.

bioRxiv · Feb 3, 2026 · PreprintNeuroscience