Author

Guofang Zhang

Duke UniversityORCID 0000-0002-4616-2721Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley S. WilliamsiD· 1 shared Chorlada PaiboonrungruangiD· 1 shared Deborah M. MuoioiD· 1 shared Dorothy H. Slentz· 1 shared Fang Lu· 1 shared Louise LantieriD· 1 shared Owen P. McGuinnessiD· 1 shared Pingchuan Tang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

Ashley S. WilliamsORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 15, 2026

Loss of Propionyl-CoA Carboxylase Reprograms Hepatic Metabolism by Suppressing Mitochondrial Pyruvate Carboxylation and Fatty Acid Oxidation

Fang Lu, Chorlada Paiboonrungruang, Wentao He…·Guofang Zhang

This study investigates metabolic changes in PCCA-deficient hepatocytes, showing reduced fatty acid oxidation and pyruvate carboxylation, leading to impaired gluconeogenesis and lipid synthesis.

DOI 10.64898/2026.04.13.718201

humanmetabolomics

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PhysiologybioRxivPreprintApr 2, 2026

A high-resolution mass spectrometry-based method for quantifying insulin-stimulated glucose uptake in mice following an intraperitoneal injection of tracer

Guofang Zhang, Dorothy H. Slentz, Louise Lantier…·Ashley S. Williams

This paper develops and validates a mass spectrometry-based method to measure insulin-stimulated tissue-specific glucose clearance in mice without radiolabels or catheters.

DOI 10.64898/2026.03.31.714892

mousemetabolomics

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