Nalan Liv

The paper shows adult human and mouse inner ear progenitor cells can generate Myosin 7A positive cells in vitro, suggesting regenerative potential for hearing loss.

This study identifies TSPAN3 as a marker of a distinct secretory multivesicular body population with unique trafficking and EV composition compared to CD63-positive compartments.

The paper identifies MARCKSL1 as a regulator of extracellular vesicle secretion pathways through a CRISPR activation screen and functional studies.

This study develops bioengineered liver tissues using multiple cell types and synthetic hydrogels, showing improved structure, function, and maturation.

This study shows that the HOPS complex recruits Rags and FLCN to lysosomal membranes, enabling non-canonical mTORC1 signaling and lysosomal biogenesis.

The paper identifies that lysosomal alkalinization under nutrient stress selects for metabolically plastic, motile cancer cells through mechanisms involving lysosomal exocytosis and sublethal apoptotic signaling.

This study shows that fasting improves PLN R14del cardiomyopathy by restoring lysosomal function and reducing SR-derived vesicle accumulation.

This paper presents an end-to-end 3D CLEM processing pipeline that integrates existing and new tools to streamline analysis, improve reproducibility, and support facility-scale use.

This study identifies the RAB32-LRMDA-Commander complex and shows its role in melanosome biogenesis and pigmentation, revealing the mechanism of oculocutaneous albinism type 7.

The paper identifies the mechanism by which SNX17 cargo is selected for entry into the Commander recycling pathway through direct binding to the Retriever sub-complex.