Author

Ning Xie

Second Affiliated Hospital of Xi'an Jiaotong UniversityORCID 0000-0002-4628-2299Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ning Xie2 papers · Affiliated Hospital of North Sichuan Medical College

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Feng Xu· 2 shared Haitao ShiiD· 2 shared Jian WuiD· 2 shared Jinhai WangiD· 2 shared Lu LiiD· 2 shared Na Liu· 2 shared Qiuai Shu· 2 shared Xiru Liang· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Feng Xu

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3 papers

Recent·Most cited

Matrix stiffness shapes immunometabolic states and response to PD-1 blockade in gastric cancer

Qiuai Shu, Jian Wu, Ziwei Wang, Yutong Cheng, Xiru Liang, Yingqi Li, Haiqiang Tao, Haitao Shi, Yuxin Peng, Bin Qin, Baicang Zou, Feng Xu, Jinhai Wang, Yongzhan Nie, Yongquan Shi, , Ning Xie

This study shows that matrix stiffness in gastric cancer affects immunometabolic states and response to PD-1 blockade, with softer matrices improving treatment efficacy.

bioRxiv · Oct 27, 2026 · PreprintCancer Biology

Persistent Post-Inflammatory Matrix Stiffening Defines a Premalignant Mechanical Niche in Ulcerative Colitis-Associated Neoplasia

Ziwei Wang, Ning Xie, Beibei Xu, Jian Wu, Bo Cheng, Yutong Cheng, Haitao Shi, Qiuai Shu, Y Li, Xiru Liang, Ameng Shi, Yuxin Peng, Bin Qin, Mingxuan Song, Kairuo Wang, , Feng Xu

This study identifies persistent post-inflammatory matrix stiffening as a premalignant mechanical niche in UC-associated neoplasia, showing its role in epithelial remodeling and potential therapeutic targeting.

bioRxiv · Jun 19, 2026 · PreprintCancer Biology

Unveiling the Biochemical Mechanisms of Aging and the Implications of Oxidative Stress on Cellular Senescence through Multi-Omics Analysis of Fibroblasts

Rema Mandal, Ning Xie, Gil Alterovitz

This study uses multi-omics analysis of human fibroblasts to show that mitochondrial dysfunction and epigenetic changes drive aging, with specific treatments affecting cellular lifespan and metabolic balance.

bioRxiv · May 17, 2025 · PreprintGenomics