Murat K. Saparbaev

Enhanced thermal stability enables human mismatch-specific thymine-DNA glycosylase to catalyse futile DNA repair

This study shows that full-length TDG, but not its catalytic domain or MBD4, can excise T and C from undamaged DNA under specific conditions, suggesting a role in futile DNA repair.

Mitochondrial mutation spectrum in Chordates: damage versus replication signatures, causes, and dynamics

The paper analyzes the mitochondrial mutation spectrum in chordates, identifying three main mutation signatures and their underlying causes, with implications for age-related disease prevention.

Chargaff's second parity rule lies at the origin of additive genetic interactions in quantitative traits to make natural selection possible.

The paper proposes that Chargaff's second parity rule underlies additive genetic interactions in quantitative traits, enabling continuous variation and natural selection.

DNA repair and mutagenesis in vertebrate mitochondria: evidence for the asymmetric DNA strand inheritance.

The paper investigates DNA repair and mutagenesis in vertebrate mitochondria, finding evidence for asymmetric DNA strand inheritance leading to strand-specific mutation patterns.