Stepan Denisov

BacNeMu reconstructs bacterial neutral mutation spectra using phylogenetic analysis and open databases, matching mutation accumulation experiments with less time.

This study shows that strong prokaryotic promoters are more mutationally robust, with robustness influenced by box spacing and sequence flexibility.

This paper introduces QMS-Seq, a high-throughput method to identify antibiotic resistance mutations in E. coli, revealing distinct mutation patterns for multi-drug and antibiotic-specific resistance.

The paper studies the conservation and evolution of intrinsic transcriptional terminators between Escherichia coli and Salmonella enterica subsp. pullorum, finding low sequence and functional conservation despite their close relation.

The paper analyzes the mitochondrial mutation spectrum in chordates, identifying three main mutation signatures and their underlying causes, with implications for age-related disease prevention.

The paper identifies 916,360 conserved long-range RNA structures in the human transcriptome and shows their association with pre-mRNA processing.

The paper presents an extended catalogue of tandem alternative splice sites in human tissues, analyzing their expression and regulation.