Developmental BiologybioRxivPreprint
Analysis of mouse lens morphological and proteomic abnormalities following depletion of βB3-crystallin
Danielle Rayêe, Phillip A. Wilmarth, Judy K. VanSlyke…·Aleš Cvekl
This study establishes a mouse model of Crybb3 loss-of-function and identifies proteomic changes in the lens, including downregulation of multiple proteins and altered transcription factor activation.
DOI 10.1101/2024.12.30.630781