Larry L. David

This study establishes a mouse model of Crybb3 loss-of-function and identifies proteomic changes in the lens, including downregulation of multiple proteins and altered transcription factor activation.

This study shows fatiguing exercise reduces cellular passive Young's modulus in male human muscle but not female, linked to titin phosphorylation changes.

This study investigates the effects of α-crystallin gene knockout on zebrafish lens development, finding that loss of A-crystallin causes lens defects while loss of Ba- or Bb-crystallin does not.

This study identifies PKCα-dependent phosphoproteins in mouse retinal rod bipolar cells using phosphoproteomics, finding BORG4 and TPBG as differentially phosphorylated proteins in synaptic layers.

This study identifies ELMOD1 as a GAP for ARF6 that stabilizes apical structures in vestibular hair cells by promoting ARF6-GTP hydrolysis.