Phillip A. Wilmarth

This paper identifies clofibric acid as a SYVN1 ligand and demonstrates its use in developing SYVN1-dependent BRD4 PROTACs with improved degradation efficiency.

This study establishes a mouse model of Crybb3 loss-of-function and identifies proteomic changes in the lens, including downregulation of multiple proteins and altered transcription factor activation.

The paper identifies dysregulated proteins in the orbitofrontal cortex of individuals with alcohol use disorder using proteomics and machine learning, linking them to drinking behavior in mice.

The paper uses deep learning and Prosit to enhance proteome profiling of grapevine vascular sap during Pierce's disease, increasing identified proteins and revealing new pathways.

This study identifies PKCα-dependent phosphoproteins in mouse retinal rod bipolar cells using phosphoproteomics, finding BORG4 and TPBG as differentially phosphorylated proteins in synaptic layers.