Claudia Carabaña

Dynamic mechanical sorting biases niche occupancy and lineage outcome during development of bilayered glandular epithelia

The paper shows that mechanical sorting, driven by adhesion and contractility differences, maintains basal-luminal compartmentalization and influences lineage outcomes in glandular epithelia.

Positional cues underlie cell fate specification during branching morphogenesis of the embryonic mammary epithelium

The paper uses single-cell RNA-sequencing to map the differentiation trajectories of mammary stem cells and identifies spatial and molecular features of lineage commitment during mammary branching morphogenesis.