Author

Amanda L. Tatler

University of NottinghamORCID 0000-0002-4644-4614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison E. JohniD· 2 shared Gisli R. JenkinsiD· 2 shared Amanda T. GoodwiniD· 1 shared Anna K. ReediD· 1 shared Anthony HabgoodiD· 1 shared Athol Umfrey WellsiD· 1 shared Bin LiuiD· 1 shared Charlotte H. DeaniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Alison E. JohnORCID

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2 papers

Recent·Most cited

Spatial multiomic profiling reveals distinct fibrotic epithelial niches in idiopathic pulmonary fibrosis

Bin Liu, Konain Bhatti, Iain D. Stewart, James Michael May, Maria Concetta Zarcone, Nathalie Lambie, Nik Matthews, Rachel L. Clifford, Charlotte H. Dean, Peter Myles George, Richard J Hewitt, Elena Ana López-Jiménez, Maddy Parsons, Simon R. Johnson, Anna K. Reed, , Alison E. John

The paper uses spatial multiomic profiling to identify distinct fibrotic epithelial niches in IPF, revealing a KRT5low/KRT17 epithelial population and its association with SPP1 macrophages.

bioRxiv · Dec 10, 2024 · PreprintMolecular Biology

Stretch Regulates Alveologenesis Via Mesenchymal Gαq/11-Mediated TGFβ2 Activation

Amanda T. Goodwin, Alison E. John, Chitra Joseph, Anthony Habgood, Amanda L. Tatler, Katalin Suszták, Matthew Palmer, Stefan Offermanns, Neil Cowan Henderson, Gisli R. Jenkins

This study shows that mesenchymal Gαq/11 signaling regulates TGFβ2 activation in response to stretch, which is critical for alveologenesis and lung homeostasis.

bioRxiv · Sep 6, 2020 · PreprintDevelopmental Biology