Author

Matthew Palmer

University of PennsylvaniaORCID 0000-0002-0534-4289Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Matthew Palmer1 paper · University of Exeter

Biology Disciplines

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Genetics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

Katalin SusztákiD· 3 shared Hongbo LiuiD· 2 shared Steven S. PulleniD· 2 shared Steven VitaleiD· 2 shared Ziyuan MaiD· 2 shared Adriana M. HungiD· 1 shared Alison E. JohniD· 1 shared Amanda L. TatleriD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersGenetics

Katalin SusztákORCID

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3 papers

Recent·Most cited

Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression

Amin Abedini, Jonathan L. Levinsohn, Konstantin A. Klötzer, Bernhard Dumoulin, Ziyuan Ma, Julia Frederick, Poonam Dhillon, Michael S. Balzer, Rojesh Shrestha, Hongbo Liu, Steven Vitale, Kishor B. Devalaraja-Narashimha, Paola Grandi, Tanmoy Bhattacharyya, Erding Hu, , Katalin Suszták

Multi-omic and spatial profiling of 81 human kidney samples resolves four tissue microenvironments; the fibrotic one's gene signature is reported to beat histopathology at predicting outcome.

bioRxiv · Oct 24, 2022 · PreprintGenetics

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, , Katalin Suszták

The paper maps genetic variants to cell types in the kidney to identify disease mechanisms and drug targets.

Nature Genetics · Aug 12, 2021Peer-reviewedGenetics

Stretch Regulates Alveologenesis Via Mesenchymal Gαq/11-Mediated TGFβ2 Activation

Amanda T. Goodwin, Alison E. John, Chitra Joseph, Anthony Habgood, Amanda L. Tatler, Katalin Suszták, Matthew Palmer, Stefan Offermanns, Neil Cowan Henderson, Gisli R. Jenkins

This study shows that mesenchymal Gαq/11 signaling regulates TGFβ2 activation in response to stretch, which is critical for alveologenesis and lung homeostasis.

bioRxiv · Sep 6, 2020 · PreprintDevelopmental Biology