Alejandra Alonso

CBD lengthens sleep, shortens ripples and leads to intact simple but worse cumulative memory

This study shows CBD extends sleep and alters NonREM oscillations in rats, improving sleep but impairing cumulative memory consolidation while leaving simple memory unaffected.

Learning Fast and Slow: Increased cortical plasticity leads to memory interference and enhanced hippocampal-cortical interactions

The paper shows that increasing cortical plasticity via RGS14414 overexpression improves one-trial memory but causes memory interference and alters hippocampal-cortical interactions.

Optogenetic stimulation of septal somatostatin neurons disrupts locomotory behavior and regulates hippocampus cholinergic theta oscillations

This study shows that optogenetic inhibition of septal somatostatin neurons disrupts goal-directed behavior and alters hippocampal theta oscillations and repetitive self-grooming.

Defensive and offensive behaviors in social interaction settings in a Kleefstra syndrome mouse model

The paper examines social interaction behaviors in Ehmt1+/- mice, finding they display defensive and offensive behaviors not seen in wild-type mice.

Schema-induced shifts in mice navigational strategies are unveiled by a minimal behavioral model of spatial exploration.

The paper analyzes mice navigation in a HexMaze to reveal how structured knowledge influences behavior, finding a combination of goal-oriented and random components in their strategies.

The Object Space Task reveals a dissociation between semantic-like and episodic-like memory in a mouse model of Kleefstra Syndrome

The paper uses the Object Space Task to show Ehmt1 +/- mice have reduced episodic-like memory and exploration but enhanced semantic-like memory, with semantic features better for genotype classification.

Basal forebrain gating by somatostatin neurons drives cortical activity

This study shows that somatostatin neurons in the basal forebrain regulate cortical activity and behavior by modulating synaptic output.