Author

Maria L. Habean

Cleveland ClinicORCID 0000-0002-4667-8883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Brandon C. SmithiD· 2 shared Jessica Lynn WilliamsiD· 2 shared Rachel A. TinkeyiD· 2 shared Arshiya MariamiD· 1 shared Orion D. BrockiD· 1 shared Ranjan DuttaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Brandon C. SmithORCID

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2 papers

Recent·Most cited

BATF2 is a regulator of interferon-gamma signaling in astrocytes during neuroinflammation

Rachel A. Tinkey, Brandon C. Smith, Maria L. Habean, Jessica Lynn Williams

The paper identifies BATF2 as a key suppressor of overactive immune signaling in astrocytes during neuroinflammation by regulating IRF1 and Caspase-1 expression.

Cell Reports · Mar 1, 2025Peer-reviewedNeuroscience

Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1

Brandon C. Smith, Rachel A. Tinkey, Orion D. Brock, Arshiya Mariam, Maria L. Habean, Ranjan Dutta, Jessica Lynn Williams

This study shows astrocytic IFN-gamma signaling reduces inflammation in MS via PD-L1, suggesting therapeutic potential.

Journal of Neuroinflammation · Oct 12, 2023Peer-reviewedNeuroscience