Author

John Simms

Aston UniversityORCID 0000-0002-4675-0902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Andrew R. PittiD· 1 shared Corinne Michelle SpickettiD· 1 shared David R. PoyneriD· 1 shared Joseph Gunner· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Andrew R. PittORCID

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1 paper

Recent·Most cited

The effect of oxidative stress on the Adenosine A2a Receptor structure, activity and signalling

Joseph Gunner, David R. Poyner, John Simms, Andrew R. Pitt, Corinne Michelle Spickett

This study investigates how oxidative stress affects the structure, activity, and signaling of the Adenosine A2a Receptor (A2aR), finding no structural impact but increased cAMP levels in response to agonists under oxidative conditions.

Biochimica et Biophysica Acta (BBA) - Biomembranes · Feb 3, 2025Peer-reviewedBiochemistry