Tianhua Ma

Pharmacological Induction of Irreversible Senescence in Drug-Tolerant Persister Cells Prevents Tumor Relapse

This paper identifies a drug combination that irreversibly senesces drug-tolerant persister cells, preventing tumor relapse in melanoma models.

Reinforced identity confers cells with cancer hallmarks

This study identifies reinforced cell identity as a driver of cancer development and demonstrates a drug targeting this identity in AML.