Author
Sage BionetworksORCID 0000-0002-4719-9120Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Sean M. Gross, Mark A. Dane, Rebecca Lee Smith…·Laura M. Heiser
The paper presents a LINCS Microenvironment perturbation dataset cataloging transcriptional, proteomic, epigenomic, and phenotypic responses of MCF10A cells to six ligands, enabling integrative analysis of molecular and phenotypic changes.
Young Hwan Chang, Jeremy W. Linsley, Josh Lamstein…·Steven M. Finkbeiner
This paper introduces a cell tracking method based on Voronoi partition and stable matching to improve tracking accuracy from coarsely sampled live-cell imaging data.
Sumit Mukherjee, Thanneer Malai Perumal, Kenneth Daily…·Benjamin A. Logsdon
The paper develops a multi-view evidence aggregation method to identify and rank potential driver genes of Alzheimer's Disease using RNA-Seq data and GWAS summary statistics.
Benjamin A. Logsdon, Thanneer Malai Perumal, Vivek Swarup…·Lara M. Mangravite
Coexpression meta-analysis of 2114 human brain RNA-seq samples across the AMP-AD consortium identifies five consensus Alzheimer's disease transcriptional clusters, including two sex-heterogeneous clusters and a previously unreported proteostasis cluster.
Timothy E. Sweeney, Thanneer Malai Perumal, Ricardo Henao…·Raymond J. Langley
The paper develops gene-expression-based prognostic models for 30-day mortality in sepsis using community-onset and hospital-acquired sepsis cohorts, showing improved prediction when combined with clinical scores.
Christina K. Yung, Brian D. O’Connor, Sergei Yakneen…·Charles L. Short
The paper describes the PCAWG project's large-scale analysis of cancer whole genomes across multiple computing environments, producing validated consensus variants for downstream research.