Author

John W. McCauley

The Francis Crick InstituteORCID 0000-0002-4744-6347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Alice LilleyiD· 1 shared Andrew Chan· 1 shared Andrew M. RamsayiD· 1 shared Basudev PaudyaliD· 1 shared Benedikt AsbachiD· 1 shared Benjamin C. MollettiD· 1 shared Benjamin Scott S SimpsoniD· 1 shared Catherine F. HattoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Alice LilleyORCID

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2 papers

Recent·Most cited

Post-infection pig and ferret antisera show similar antigenic profiles for human influenza A(H1N1pdm09) viruses

Ruth Harvey, Tiphaine Cayol, Basudev Paudyal, Alice Lilley, Christine Carr, Catherine F. Hatton, Emily Briggs, Rodney Stuart Daniels, Samuel Richardson, Thomas P. Peacock, Nicola S. Lewis, Ian Hay Brown, John W. McCauley, Elma Z. Tchilian

This study compares antigenic profiles of post-infection antisera from pigs and ferrets against human influenza A(H1N1pdm09) viruses, finding similar reactivity but limitations in detecting antigenic drift variants.

Influenza and Other Respiratory Viruses · Apr 1, 2026Peer-reviewedImmunology

Immunogenicity and Efficacy of Digitally Immune Optimised H1N1 Vaccine Candidates in Swine and Murine Animal Models

Joanne Marie M. Del Rosario, Pauline M. van Diemen, Simon D. W. Frost, Sneha Vishwanath, Sneha B Sujit, Sruthika K. Ashokan, Benjamin C. Mollett, Andrew M. Ramsay, Benjamin Scott S Simpson, Benedikt Asbach, George Carnell, Andrew Chan, Paul Tonks, Nigel James Temperton, Matthew Davies, , Jonathan Luke Heeney

This paper demonstrates the immunogenicity and efficacy of a computationally designed DNA vaccine against H1N1 influenza in swine and mice, showing broad neutralizing antibody responses and reduced viral shedding.

bioRxiv · Sep 12, 2025 · PreprintImmunology