Systems BiologybioRxivPreprint
Probability-based detection of phosphoproteomic uncertainty reveals rare signaling events driven by oncogenic kinase gene fusion
Xavier Robin, Franziska Völlmy, Jesper Ferkinghoff‐Borg…·Rune Linding
The paper introduces a Bayesian method to estimate protein concentrations and phosphorylation site occupancy ratios from mass spectrometry data, applied to study PRKAR1A-RET gene fusion effects.
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