Franziska Völlmy

This study reveals how ARID1A-mediated transcriptional rewiring drives resistance to MAPK inhibitors in melanoma by altering signalling pathways, immune interactions, and receptor dynamics, highlighting potential targets for combinatorial therapies.

This study tracks longitudinal changes in the plasma proteome and complexome of kidney failure patients before and after transplantation, revealing acute phase protein dynamics and macromolecular complex formation during inflammation.

This study shows that PIK3CAH1047R homozygosity in hPSCs leads to self-sustained stemness via enhanced NODAL/TGFβ signalling, which can be reversed by TGFβ inhibition.

The paper introduces a Bayesian method to estimate protein concentrations and phosphorylation site occupancy ratios from mass spectrometry data, applied to study PRKAR1A-RET gene fusion effects.