GenomicsbioRxivPreprint
Deep learning modeling of ribosome profiling reveals regulatory underpinnings of translatome and interprets disease variants
Jialin He, Lei Xiong, Shaohui Shi…·Xushen Xiong
The paper introduces Translatomer, a transformer model that predicts cell-type-specific translation from mRNA and sequence data, identifies disease variants affecting translation, and reveals non-eQTL regulatory mechanisms.