Josune Imaz-Iruretagoyena

RNA binding protein IMP1/ZBP1 drives Actb mRNA localization and local translation in microglial peripheral processes and mediates morphological changes, motility and phagocytosis in response to inflammation

The paper investigates local translation in microglial peripheral processes and shows that IMP1/ZBP1 regulates Actb mRNA localization and translation, affecting microglial morphology and function during inflammation.

Object-based analyses in FIJI/ImageJ to measure local RNA translation sites in neurites in response to Aβ1-42 oligomers

The paper describes an object-based analysis in FIJI/ImageJ to quantify local RNA translation sites in neurites and shows Aβ1-42 increases local protein synthesis.