Cancer BiologybioRxivPreprint
Loss of the Y chromosome drives epigenetic and transcriptomic plasticity in lung adenocarcinoma
Kathleen Schlüter, Mei-Ju May Chen, Gizem Altun…·Maria Llamazares Prada
This study shows that loss of the Y chromosome in lung adenocarcinoma causes epigenetic and transcriptomic changes that increase lineage plasticity and poor clinical outcomes.
DOI 10.64898/2026.06.02.729627