Author

Ke Zhang

Mayo ClinicORCID 0000-0002-4794-8355Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ke Zhang4 papers · Jiangnan University

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Angelina Li· 1 shared Brian J. LeeiD· 1 shared Chaolin ZhangiD· 1 shared Daniel F. MoakleyiD· 1 shared Fei HouiD· 1 shared Feilin LiuiD· 1 shared Jimin Yoon· 1 shared Jing DuaniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Angelina Li

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2 papers

Recent·Most cited

Primate-specific adaptation of Ku protects transcriptomic integrity by suppressing Alu-mediated alternative splicing

Tianji Yu, Jimin Yoon, Yimeng Zhu, Angelina Li, Brian J. Lee, Daniel F. Moakley, Jing Duan, Qiannian Deng, Fei Hou, Mengfang Yan, Vincenzo Alessandro Gennarino, Ke Zhang, Li Chen, Shan Zha, Chaolin Zhang

This study shows that primate-specific Ku adaptation suppresses Alu-mediated alternative splicing, maintaining transcriptomic integrity and linking Ku function to brain development and disease.

bioRxiv · Dec 18, 2025 · PreprintMolecular Biology

C-Jun N-terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-mediated ALS and FTD

T. G. Sahana, Katherine Johnson Chase, Feilin Liu, Thomas E. Lloyd, Wilfried Rossoll, Ke Zhang

This study shows that JNK activation by ER stress promotes SG assembly and neurodegeneration in C9orf72-mediated ALS/FTD through G3BP1 transcription.

Journal of Neuroscience · Apr 4, 2023Peer-reviewedNeuroscience