Author
Johns Hopkins UniversityORCID 0000-0003-4756-3700Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Sarah E. Maguire, Joel J. Credle, Elizabeth Bertelson…·H. Benjamin Larman
This paper introduces a method for high-plex spatial transcriptomics using dual probe ligation and rolling-circle amplification to analyze FFPE tissues.
Eileen M. Lynch, Sara K. Pittman, Jil Daw…·Conrad Chris Weihl
This study shows that TDP-43 aggregate seeds persist in both mouse and human skeletal muscle even after the removal of large TDP-43 inclusions.
T. G. Sahana, Katherine Johnson Chase, Feilin Liu…·Ke Zhang
This study shows that JNK activation by ER stress promotes SG assembly and neurodegeneration in C9orf72-mediated ALS/FTD through G3BP1 transcription.
Hong Joo Kim, Payam Mohassel, Sandra C. Donkervoort…·J. Paul Taylor
The paper identifies heterozygous frameshift variants in hnRNPA2B1 causing early-onset oculopharyngeal muscular dystrophy by altering nucleocytoplasmic transport.
Loren Ornelas, Emilda Gomez, Lindsay Panther…·Leslie Michels Thompson
The paper performs an integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients to identify dysregulated pathways and validate them in vivo and in postmortem data.