C-Jun N-terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-mediated ALS and FTD
T. G. Sahana, Katherine Johnson Chase, Feilin Liu, Thomas E. Lloyd, Wilfried Rossoll, Ke Zhang
This study shows that JNK activation by ER stress promotes SG assembly and neurodegeneration in C9orf72-mediated ALS/FTD through G3BP1 transcription.
Journal of Neuroscience · Apr 4, 2023Peer-reviewedNeuroscience