Author

Philipp Lohneis

University of CologneORCID 0000-0002-4797-0018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander QuaasiD· 1 shared Alfred Christian Feller· 1 shared Anke FähnrichiD· 1 shared Annika RaschdorfiD· 1 shared Axel Karl WalchiD· 1 shared Axel KünstneriD· 1 shared Benedikt Faerber· 1 shared Christiane J. BrunsiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alexander QuaasORCID

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2 papers

Recent·Most cited

PD-L1-linked spatial decoupling of tumour-immune interactions in EBV-positive DLBCL

Axel Künstner, Matthias Kümmel, Anke Fähnrich, Stefanie Derer, Annika Raschdorf, Hanno Maximilian Witte, Yamil Maluje, Benedikt Faerber, Thies Rösner, Lisa Michelson, Friederike Stiller, Mona Maria Merz, Veronica Bernard, Stephanie Stoelting, Daniel Kolbe, , Niklas Gebauer

The paper investigates how PD-L1 genomic gains in EBV-positive DLBCL alter spatial tumour-immune interactions, revealing immune evasion through fibroblast exclusion, metabolic suppression, and T-cell exhaustion.

medRxiv · Jul 4, 2026 · PreprintGenetic & Genomic Medicine

Predicting the HER2 status in esophageal cancer from tissue microarrays using convolutional neural networks

Juan I. Pisula, Rabi Raj Datta, Leandra Börner Valdez, Jan-Robert Avemarg, Jin‐On Jung, Patrick Sven Plum, Heike Löser, Philipp Lohneis, Monique Meuschke, Daniel Pinto dos Santos, Florian Gebauer, Alexander Quaas, Christiane J. Bruns, Axel Karl Walch, Kai Lawonn, , Katarzyna Bożek

This paper develops a CNN-based method to predict HER2 status in esophageal cancer tissue microarrays with high accuracy, outperforming manual assessment and reducing the need for costly follow-up tests.

bioRxiv · May 13, 2022 · PreprintBioinformatics