Author

Zeng‐Guang Xu

Tongji UniversityORCID 0000-0002-4814-9635Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:deep learning· 1 Organism:non-human primate· 1 Organism:zebrafish· 1

Frequent Co-Authors

Zhan‐Yun GuoiD· 4 shared Jie YuiD· 3 shared Wenfeng HuiD· 3 shared Y.-L. LiuiD· 3 shared Juan-Juan Wang· 2 shared Yong‐Shan Zheng· 2 shared Cheng HeiD· 1 shared Juanjuan WangiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBiochemistry

Zhan‐Yun GuoORCID

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4 papers

Recent·Most cited

BiochemistryArchives of Biochemistry and BiophysicsPeer-reviewedOct 28, 2025

CXCL17 activates three MAS-related G protein-coupled receptors independently of its conserved C-terminal fragment

Wenfeng Hu, Juan-Juan Wang, Jie Yu…·Zhan‐Yun Guo

This study confirms that CXCL17 activates MRGPRX2, MRGPRX1, and MAS1 independently of its C-terminal fragment, unlike its effect on GPR25.

7 citations

humanexperimental assay

BiochemistryBiochimiePeer-reviewedSep 17, 2025

Human CXCL17 Activates and Binds to Fish GPR25 Orthologs

Wenfeng Hu, Juan-Juan Wang, Jie Yu…·Zhan‐Yun Guo

This study shows human CXCL17 activates and binds to fish GPR25 orthologs, suggesting conservation of the CXCL17-GPR25 interaction across vertebrates.

7 citations

BiochemistryFEBS JournalPeer-reviewedApr 25, 2025

Identification of the orphan GPR25 as a receptor of the chemokine CXCL17

Wenfeng Hu, Jie Yu, Juanjuan Wang…·Zhan‐Yun Guo

This study identifies GPR25 as the receptor for CXCL17 using AlphaFold 3 prediction and NanoBiT-based assays, showing specific activation and structural binding.

15 citationstop 3%

humanproteomics

BiochemistryBiochemical and Biophysical Research CommunicationsPeer-reviewedMar 10, 2024

Is myeloid-derived growth factor a ligand of the sphingosine-1-phosphate receptor 2?

Yong‐Shan Zheng, Y.-L. Liu, Zeng‐Guang Xu…·Zhan‐Yun Guo

The paper tests if MYDGF is a ligand for S1PR2 using functional assays and finds it is not.

5 citations

humanexperimental assay