Author

Wenfeng Hu

Tongji UniversityORCID 0000-0002-2571-3889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:zebrafish· 2 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jie YuiD· 4 shared Zhan‐Yun GuoiD· 4 shared Juan-Juan Wang· 3 shared Zeng‐Guang XuiD· 3 shared Y.-L. LiuiD· 2 shared Juanjuan WangiD· 1 shared Jun-Jie Yao· 1 shared Ru‐Jiao Sun· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBiochemistry

Jie YuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification and functional characterization of two CXCL17 paralogs from zebrafish

Jie Yu, Wenfeng Hu, Juan-Juan Wang, Ya-Li Liu, XU Zeng-guang, Zhan‐Yun Guo

This study identifies and functionally characterizes two CXCL17 paralogs in zebrafish, showing they bind and activate GPR25 and induce chemotaxis.

Biochemical Journal · Jan 12, 2026Peer-reviewedBiochemistry

CXCL17 activates three MAS-related G protein-coupled receptors independently of its conserved C-terminal fragment

Wenfeng Hu, Juan-Juan Wang, Jie Yu, Yali Liu, Zeng‐Guang Xu, Zhan‐Yun Guo

This study confirms that CXCL17 activates MRGPRX2, MRGPRX1, and MAS1 independently of its C-terminal fragment, unlike its effect on GPR25.

Archives of Biochemistry and Biophysics · Oct 28, 2025Peer-reviewedBiochemistry

Human CXCL17 Activates and Binds to Fish GPR25 Orthologs

Wenfeng Hu, Juan-Juan Wang, Jie Yu, Jun-Jie Yao, Yali Liu, Zeng‐Guang Xu, Zhan‐Yun Guo

This study shows human CXCL17 activates and binds to fish GPR25 orthologs, suggesting conservation of the CXCL17-GPR25 interaction across vertebrates.

Biochimie · Sep 17, 2025Peer-reviewedBiochemistry

Identification of the orphan GPR25 as a receptor of the chemokine CXCL17

Wenfeng Hu, Jie Yu, Juanjuan Wang, Ru‐Jiao Sun, Yong‐Shan Zheng, Teng Zhang, Y.-L. Liu, Zeng‐Guang Xu, Zhan‐Yun Guo

This study identifies GPR25 as the receptor for CXCL17 using AlphaFold 3 prediction and NanoBiT-based assays, showing specific activation and structural binding.

FEBS Journal · Apr 25, 2025Peer-reviewedBiochemistry