Author

Zoey R. Litt

University of WashingtonORCID 0009-0000-6513-7583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Afredo Ruiz-RiveraiD· 2 shared Alexey J. MerziD· 2 shared Angela LisovskyiD· 2 shared Beth A. TraxleriD· 2 shared Emma Y.D. MilleriD· 2 shared Justin N. ApplegateiD· 2 shared Andrea Elizabeth WillsiD· 1 shared Audrey G. O’NeilliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Afredo Ruiz-RiveraORCID

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3 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedAug 31, 2026

β-strand complementation within tip initiation complexes licenses assembly of diverse type IV filaments

Taylor J. Ellison, Zoey R. Litt, Justin N. Applegate…·Alexey J. Merz

This paper identifies a β-strand complementation mechanism used by PilC/PilY1 proteins to license type IV filament assembly across diverse systems.

DOI 10.1073/pnas.2602298123

𝕏 PostBluesky

MicrobiologybioRxivPreprintFeb 9, 2026

Expression of soluble Type IV Minor Pilins and isolation of a Neisseria gonorrhoeae PilI-PilJ subcomplex

Justin N. Applegate, Emma Y.D. Miller, Zoey R. Litt…·Alexey J. Merz

This paper describes a method to express and purify soluble type IV minor pilins from E. coli and identifies a heterodimeric interaction between PilI and PilJ in Neisseria gonorrhoeae.

1 citation

E. coliproteomics

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Developmental BiologybioRxivPreprintJul 29, 2024

Appendage regeneration requires IMPDH2 and creates a sensitized environment for enzyme filament formation

Morgan E. McCartney, Gavin M. Wheeler, Audrey G. O’Neill…·Andrea Elizabeth Wills

The paper shows that IMPDH2 is required for tail regeneration in Xenopus tropicalis and forms filaments in regenerating tissue under high GTP demand.

2 citations

mouseexperimental assay

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