Swagat Sharma

This paper develops a nanotherapy to reprogram antigen-presenting cells and induce T cell anergy, delaying type 1 diabetes onset in mice.

This paper develops a composite hydrogel (C-gel) that enables localized in situ gelation and sustained nanocarrier release in the anterior chamber of the eye, showing 90% polymer retention and over a month of sustained release in mice.

The paper demonstrates that synthetic nanocarriers deliver RAS-degrading mRNA to pancreatic tumors, reducing RAS levels and tumor growth.