Author

Anthony J. Asmar

National Institutes of HealthORCID 0000-0002-4843-0785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Achim A WerneriD· 2 shared David B. BeckiD· 2 shared Adele P. PeskiniD· 1 shared Andrew D. DoyleiD· 1 shared Anne L. PlantiD· 1 shared Apratim MitraiD· 1 shared Cynthia J. TifftiD· 1 shared Daniel L. KastneriD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersDevelopmental Biology

Achim A WernerORCID

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3 papers

Recent·Most cited

High-volume, label-free imaging for quantifying single-cell dynamics in induced pluripotent stem cell colonies

Anthony J. Asmar, Zackery A. Benson, Adele P. Peskin, Joe Chalfoun, Mylene Simon, Michael W. Halter, Anne L. Plant

The paper develops an AI pipeline for analyzing phase contrast images of iPSC colonies to track cell dynamics without labeling.

PLoS ONE · Feb 20, 2024Peer-reviewedSystems Biology

A tissue-specific ubiquitin switch coordinates brain, craniofacial, and skin development

Anthony J. Asmar, Rita M. Yazejian, Youmei Wu, Jason C. Collins, Jenny Hsin, Jean Cho, Andrew D. Doyle, Samhitha Cinthala, Marleen Simon, Richard H. van Jaarsveld, David B. Beck, Laura Kerosuo, Achim A Werner

The paper identifies a ubiquitin switch mechanism that regulates CDC42 signaling to coordinate ectodermal patterning in vertebrate development.

bioRxiv · Sep 26, 2022 · PreprintDevelopmental Biology

Regulation of human development by ubiquitin chain editing of chromatin remodelers

David B. Beck, Mohammed Abul Basar, Anthony J. Asmar, Joyce J. Thompson, Hirotsugu Oda, Daniela Tiaki Uehara, Ken Saida, Precilla D’Souza, Joann Norma Bodurtha, Weiyi Mu, Kristin W. Baranano, Noriko Miyake, Raymond Wang, Marlies J. E. Kempers, Yutaka Nishimura, , Achim A Werner

This study identifies OTUD5 as essential for chromatin remodeling during development, showing its role in preventing degradation of chromatin regulators and maintaining proper gene expression networks.

bioRxiv · Jan 23, 2020 · PreprintGenetics