Author
National Institutes of HealthORCID 0000-0003-1051-8447Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Samuel J. Magaziner, Jason C. Collins, Brecca Miller…·David B. Beck
This study identifies cGAS-STING pathway activation as a key mechanism of inflammation in VEXAS, showing that UBA1 mutations disrupt ERAD and mitochondrial homeostasis, leading to STING-driven inflammation.
Anthony J. Asmar, Rita M. Yazejian, Youmei Wu…·Achim A Werner
The paper identifies a ubiquitin switch mechanism that regulates CDC42 signaling to coordinate ectodermal patterning in vertebrate development.
David B. Beck, Mohammed Abul Basar, Anthony J. Asmar…·Achim A Werner
This study identifies OTUD5 as essential for chromatin remodeling during development, showing its role in preventing degradation of chromatin regulators and maintaining proper gene expression networks.