Laura Kerosuo

The paper shows that a Pkhd1 deletion in mice causes glaucoma by disrupting Tfap2b expression, linking PKHD1 SNPs to human glaucoma.

The paper analyzes single-cell RNA sequencing data from chick midbrain development to uncover gene regulatory networks and signaling interactions shaping ectodermal patterning.

The paper uses human ectodermal organoids to study DiGeorge Syndrome, showing defects in neural crest development and identifying key genes involved.

The paper identifies a ubiquitin switch mechanism that regulates CDC42 signaling to coordinate ectodermal patterning in vertebrate development.

This paper develops a method to maintain trunk neural crest cells as crestospheres in vitro and shows they retain stem-like properties and express trunk-specific markers.