Author

Minmin Liu

Van Andel InstituteORCID 0000-0002-7405-8972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Evan J. WordeniD· 2 shared Peter A. JonesiD· 2 shared X. Edward ZhouiD· 2 shared Di LuiD· 1 shared Gan‐Qiang LaiiD· 1 shared Huadie LiuiD· 1 shared Ji LiaoiD· 1 shared Michelle L. Dykstra· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMolecular Biology

Evan J. WordenORCID

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3 papers

Recent·Most cited

Molecular Mechanisms of DNMT3A-3L-Mediated de novo DNA Methylation on Chromatin

Yan Yan, X. Edward Zhou, Stacey L. Thomas, Minmin Liu, Gan‐Qiang Lai, Evan J. Worden, Peter A. Jones, Ting-Hai Xu

This study reveals the molecular mechanism of DNMT3A-3L-mediated de novo DNA methylation through structural analysis of its chromatin interactions and regulatory dynamics.

Nature Structural & Molecular Biology · Oct 31, 2025Peer-reviewedMolecular Biology

EHMT2 Controls Neural Crest-Derived Craniofacial Development but is Dispensable in Limb Development

Ye Liu, Yaguang Zhao, Minmin Liu, Paul Kim, Ji Liao, Di Lu, Huadie Liu, Piroska E. Szabó, Tao Yang

This study shows EHMT2 is essential for neural crest-derived craniofacial development but not for limb development.

bioRxiv · Sep 7, 2025 · PreprintCell Biology

The structural basis for de novo DNA methylation in chromatin

Xiaoyan Xie, Minmin Liu, X. Edward Zhou, Michelle L. Dykstra, Peter A. Jones, Evan J. Worden

This study reports Cryo-EM structures of DNMT3A2/3B3 bound to di-nucleosomes, revealing how linker length and H3K36 methylation influence DNA methylation.

bioRxiv · Dec 19, 2024 · PreprintBiophysics